β-Nicotinamide Mononucleotide CAS 1094-61-7

    β -nicotinamide mononucleotide, also known as β -nicotinamide mononucleotide (NMN), is a synthetic substrate of coenzyme I, and NMN is also used in anti-aging studies. Keio University in Japan and the University of Washington in the United States are conducting human clinical trials on the anti-aging effects and safety of β-NMN. Studies have shown that β-NMN can also regulate the secretion of insulin and affect the expression level of mRNA. β -chemical BooKNMn has a wide application prospect in the field of medical treatment. β -nicotinamide mononucleotide is a product of extracellular nicotinamide phosphate ribotransferase (eNAMPT) reaction and a key NAD+ intermediate. It improves glucose tolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances liver insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response and circadian rhythm, partly through SIRT1 activation.