tert-Butyl bromoacetate C6H11BrO2 CAS 5292-43-3

tert-Butyl bromoacetate Basic information

Product Name: tert-Butyl bromoacetate
Synonyms: T-BUTYL BROMOACETATE;1,1-Dimethylethyl 2-bromoacetate;1,1-Dimethylethyl bromoacetate;bromoacetic acid T-butyl ester;tertiary butyl bromoacetate;2-Bromoacetic acid-t-butylester;#ntert.-Butyl bromoacetate;tert-Butylbromoacetate,98%
CAS: 5292-43-3
MF: C6H11BrO2
MW: 195.05

tert-Butyl bromoacetate Chemical Properties

Melting point	44-47 °C
Boiling point	50 °C10 mm Hg(lit.)
density	1.338
vapor pressure	1.62hPa at 25℃
MF

     tert-Butyl Bromoacetate is a halogenated t-butyl acetate commonly used as an alkylating agent. tert-Butyl Bromoacetate is used in the synthesis of collagenase inhibitors.

     tert-Butyl bromoacetate is used as an intermediate in the production of dyes, pharmaceuticals, agrochemicals and in organic compounds. It finds application as an alkylating agent. It plays an important role to prepare (2-oxo-4-vinyl-azetidin-1-yl)-acetic acid tert-butyl ester and in collagenase inhibitors synthesis.

tert-Butyl bromoacetate has been used in the synthesis of:
nitrilotriacetic acid end-functionalized polystyrene by atom transfer radical polymerization
building block for substituted t-butyl acetates
dihydropyranyl prelinker which is useful in polymer-assisted deprotection of oligosacchararides
collagenase inhibitor (S,S,R)-(-)-actinonin It is the starting reagent for the synthesis of N-Oxalylglycine derivatives.